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Structure of 154150-18-2
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tert-Butyl (2-methoxyphenyl)carbamate delivers a protected amine handle with enhanced solubility and stability. The ortho-methoxy group modulates electronic properties, while the tert-butyl carbamate moiety ensures robust protection under standard conditions. This compound integrates seamlessly into peptide synthesis and medicinal chemistry workflows, enabling efficient deprotection with mild acid.
tert-Butyl (2-methoxyphenyl)carbamate serves as a stable, bench-friendly amino protecting group for aniline derivatives, enabling selective N-alkylation and coupling reactions under mild conditions. Its ortho-methoxy substituent enhances solubility and facilitates orthogonal deprotection in multistep syntheses. The carbamate functionality is compatible with standard hydrogenolysis and acidolytic cleavage protocols, making it well-suited for the construction of complex heterocyclic scaffolds and peptide-like architectures in medicinal chemistry workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: