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CS-W001157 4
Total: USD 88.00

o-Anisidine hydrochloride

  • CAS No. 134-29-2

  • Cat. No. CS-0150305
  • Purity≥97%
  • MDL No.MFCD00054334

*For research and further manufacturing use only, not for direct human use.

o-Anisidine hydrochloride|CS-0150305

Structure of 134-29-2

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General Information

  • CAS No. 134-29-2
  • Cat. No. CS-0150305
  • Purity ≥97%
  • MDL No. MFCD00054334
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₁₀ClNO
  • Molecular Weight 159.61
  • Synonym(s) o-Methoxyaniline (hydrochloride); o-Methoxyphenylamine (hydrochloride)
  • SMILES COC1=CC=CC=C1N.Cl

Description

2-Methoxyaniline hydrochloride is a bench-stable, moisture-tolerant amine salt featuring a para-methoxy substituent that enhances electron density at the aromatic ring. This functional group combination enables direct incorporation into coupling reactions and facilitates efficient access to substituted anilines under mild conditions.

Application

2-Methoxyaniline hydrochloride serves as a stable, bench-ready building block for the synthesis of heterocyclic scaffolds and pharmaceutical intermediates. Its aniline functionality enables direct coupling reactions, while the methoxy group provides moderate electron-donating character and ortho-directing effects. The hydrochloride salt enhances solubility and purity in standard synthetic workflows, facilitating efficient amide formation, Ullmann-type couplings, and electrophilic aromatic substitutions.

Safety Information

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GHS Pictogram :
GHS No : GHS06,GHS08
Signal Word : Danger
UN#: 2431
Class : 6.1
Packing Group : Ⅲ
Hazard Statements : H301+H311+H331-H341-H350
Precautionary Statements : P261-P280-P302+P352-P304+P340

Quality Control

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Computational Chemistry Data

  • TPSA   35.25
  • LogP   1.6992
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   1

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