Lot numbers can be found on the outside label of a product:
Boc-N-Ethylglycine
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CAS No. 149794-10-5
- Cat. No. CS-0043102
- Purity≥97%
- MDL No.MFCD00672508
*For research and further manufacturing use only, not for direct human use.
Structure of 149794-10-5
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General Information
- CAS No. 149794-10-5
- Cat. No. CS-0043102
- Purity ≥97%
- MDL No. MFCD00672508
- Storage 4°C
- Shipping Room temperature in continental US; may vary elsewhere.
- Molecular Formula C₉H₁₇NO₄
- Molecular Weight 203.24
- Synonym(s) None
- SMILES O=C(O)CN(C(OC(C)(C)C)=O)CC
Description
Boc-N-Ethylglycine features a protected amine and ethyl-substituted glycine backbone, enabling stable incorporation into peptide synthesis workflows. This bench-stable derivative simplifies N-terminal capping and facilitates the construction of sterically defined peptide segments with minimal side reactions.
Application
Boc-N-Ethylglycine serves as a versatile building block in peptide synthesis and medicinal chemistry, offering a protected α-amino acid with enhanced solubility and stability. The Boc group provides reliable N-protecting functionality, enabling efficient coupling reactions without epimerization. Its ethyl side chain imparts favorable steric and electronic properties for incorporation into bioactive scaffolds. This reagent facilitates straightforward deprotection under mild acidic conditions and is well-suited for solid-phase and solution-phase synthesis workflows.
Synthesis
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Route1
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In-stock
4530-20-5 -
75-03-6 - ~99%
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In-stock
149794-10-5
References
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GENENTECH, INC. Patent: WO2008/79735 A1, 2008 ; Location in patent: Page/Page column 45 ; WO 2008/079735 A1
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References
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H. Lundbeck A/S Patent: US2006/79524 A1, 2006 ; Location in patent: Page/Page column 13 ; US 20060079524 A1
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References
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US2008/125614 A1, ;
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Safety Information
Download SDS|
GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Quality Control
Computational Chemistry Data
- TPSA 66.84
- LogP 1.328
- H_Acceptors 3
- H_Donors 1
- Rotatable_Bonds 3
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Key Words
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