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N-Ethyl-N-methylglycine

  • CAS No. 740792-70-5

  • Cat. No. CS-0144155
  • Molecule weight117.15
  • Purity≥95%
  • MDL No.MFCD10686552

*For research and further manufacturing use only, not for direct human use.

N-Ethyl-N-methylglycine|CS-0144155

Structure of 740792-70-5

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General Information

  • CAS No. 740792-70-5
  • Cat. No. CS-0144155
  • Purity ≥95%
  • MDL No. MFCD10686552
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₁₁NO₂
  • Molecular Weight 117.15
  • Synonym(s) Albb-004039
  • SMILES O=C(O)CN(CC)C

Description

N-Ethyl-N-methylglycine offers a compact, sterically hindered zwitterionic scaffold ideal for peptide conjugation and bioconjugate design. This stable, moisture-tolerant building block integrates readily into synthetic sequences, enabling efficient access to functionalized biomolecules under standard conditions.

Application

N-Ethyl-N-methylglycine serves as a stable, synthetically accessible glycine surrogate with enhanced lipophilicity and metabolic resistance. It functions as a versatile building block in peptide-like scaffolds and bioactive molecule synthesis, enabling improved membrane permeability and pharmacokinetic profiles. The molecule's tertiary amine and α-alkylated structure facilitate compatibility with standard coupling protocols and tolerate diverse functional groups, making it suitable for medicinal chemistry campaigns requiring robust, non-peptidic motifs.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   40.54
  • LogP   0.0227
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   3

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