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Structure of 149506-16-1
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This cyclobutanecarboxylic acid derivative features a para-brominated phenyl group, offering enhanced electron-withdrawing character and improved solubility in organic media. The rigid cyclobutane scaffold provides conformational stability, facilitating efficient incorporation into bioactive scaffolds. Ideal for medicinal chemistry campaigns requiring halogenated aromatic motifs with defined steric profiles.
3-(4-Bromophenyl)cyclobutanecarboxylic acid serves as a versatile building block for the synthesis of biaryl-containing cyclobutane scaffolds. Its brominated aromatic ring enables palladium-catalyzed cross-coupling reactions, while the cyclobutanecarboxylic acid moiety provides a rigid, sterically constrained core suitable for medicinal chemistry applications. The compound exhibits good bench stability and facilitates straightforward functionalization via standard esterification or amidation protocols.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P280-P302+P352
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Lot numbers can be found on the outside label of a product: