Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

3-(2,3-Dihydro-1,4-benzodioxin-6-yl)propanoic acid

  • CAS No. 14939-92-5

  • Cat. No. CS-0215386
  • Molecule weight208.21
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

3-(2,3-Dihydro-1,4-benzodioxin-6-yl)propanoic acid|CS-0215386

Structure of 14939-92-5

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 14939-92-5
  • Cat. No. CS-0215386
  • Purity ≥98%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₁₂O₄
  • Molecular Weight 208.21
  • Synonym(s) None
  • SMILES C1=CC2=C(C=C1CCC(=O)O)OCCO2

Description

This propanoic acid derivative features a 2,3-dihydro-1,4-benzodioxin ring system that imparts enhanced solubility and metabolic stability. The aromatic ether linkage provides rigidity and electron-donating character, enabling efficient incorporation into bioactive scaffolds for medicinal chemistry applications.

Application

3-(2,3-Dihydro-1,4-benzodioxin-6-yl)propanoic acid serves as a versatile building block for bioactive molecule synthesis, offering a rigidified aromatic core with pendant carboxylic acid functionality. Its structure enables straightforward derivatization via esterification, amide coupling, or decarboxylation protocols. The 1,4-benzodioxine moiety provides metabolic stability and favorable lipophilicity, making it valuable in medicinal chemistry campaigns targeting CNS agents and kinase inhibitors. Bench-stable and readily purified by crystallization or flash chromatography, it supports scalable synthesis workflows.

Synthesis

  • Route1
    • In-stock
      Dihydrocaffeic acid|CS-0022607
      1078-61-1
    • null|null
      106-93-4
    • ~%
    • In-stock
      3-(2,3-Dihydro-1,4-benzodioxin-6-yl)propanoic acid|CS-0215386
      14939-92-5

    References

    • Eli Lilly and Company Patent: US3962282 A1, 1976 ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   55.76
  • LogP   1.475
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   3

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 14939-92-5 sigma14939-92-5 manufacturer14939-92-5 price14939-92-5 structure14939-92-5 SDSbuy 14939-92-514939-92-5 supplier14939-92-5 uses14939-92-5 molecular weightprice of 14939-92-514939-92-5 chemical name formula of 14939-92-5
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label