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CS-W001157 4
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5-(3-Bromophenyl)-1H-pyrazol-3-amine

  • CAS No. 149246-81-1

  • Cat. No. CS-0146995
  • Molecule weight238.08
  • Purity≥98%
  • MDL No.MFCD06738756

*For research and further manufacturing use only, not for direct human use.

5-(3-Bromophenyl)-1H-pyrazol-3-amine|CS-0146995

Structure of 149246-81-1

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General Information

  • CAS No. 149246-81-1
  • Cat. No. CS-0146995
  • Purity ≥98%
  • MDL No. MFCD06738756
  • Storage Sealed in dry,2-8℃
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₈BrN₃
  • Molecular Weight 238.08
  • Synonym(s) 5-(3-BROMO-PHENYL)-2H-PYRAZOL-3-YLAMINE
  • SMILES BrC1=CC(C2=CC(N)=NN2)=CC=C1

Synthesis

  • Route1

    References

    • BRISTOL-MYERS SQUIBB COMPANY; NAIDU, B. Narasimhulu; PATEL, Manoj; D'ANDREA, Stanley; ZHENG, Zhizhen Barbara; CONNOLLY, Timothy P.; LANGLEY, David R.; PEESE, Kevin; WANG, Zhongyu; WALKER, Michael A.; KADOW, John F. Patent: WO2014/28384 A1, 2014 ; Location in patent: Page/Page column 25 ;
  • Route2
    • (Z)-3-(3-bromophenyl)-3-chloroacrylonitrile|CS-0570611
      948883-31-6
    • ~54%
    • 5-(3-Bromophenyl)-1H-pyrazol-3-amine|CS-0146995
      149246-81-1

    References

    • SIENA BIOTECH S.P.A.; WYETH PHARMACEUTICALS Patent: WO2007/98826 A2, 2007 ; Location in patent: Page/Page column 50 ; WO 2007/098826 A2
  • Route3

    References

    • Journal of Organic Chemistry, , vol. 72, # 3 p. 1043 - 1046

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS06
Signal Word : Danger
UN#: 2811
Class : 6.1
Packing Group : Ⅲ
Hazard Statements : H301
Precautionary Statements : P264-P270-P330-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   54.7
  • LogP   2.4214
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   1

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