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Structure of 78583-82-1
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5-(4-Bromophenyl)-1H-pyrazol-3-amine features a brominated phenyl group attached to a pyrazole core, delivering enhanced electron-withdrawing character and enabling direct functionalization in cross-coupling reactions. The amine handle facilitates conjugation, while the scaffold exhibits robust stability under standard conditions.
5-(4-Bromophenyl)-1H-pyrazol-3-amine serves as a versatile building block for the synthesis of functionalized pyrazole-based scaffolds. Its bromo substituent enables palladium-catalyzed cross-coupling reactions, facilitating the construction of biaryl architectures. The pyrazole nitrogen supports diverse derivatization and acts as a hydrogen-bonding donor in target-directed synthesis. Bench-stable and amenable to standard purification techniques, it functions effectively in medicinal chemistry campaigns requiring modular heterocycle elaboration.
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GHS Pictogram :
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GHS No : GHS05,GHS07
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Signal Word : Danger
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UN#: 3261
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Class : 8
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Packing Group : Ⅲ
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Hazard Statements : H302-H315-H318-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: