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tert-Butyl (7-azaspiro[3.5]nonan-2-yl)carbamate

  • CAS No. 147611-03-8

  • Cat. No. CS-0041621
  • Purity≥98%
  • MDL No.MFCD12198553

*For research and further manufacturing use only, not for direct human use.

tert-Butyl (7-azaspiro[3.5]nonan-2-yl)carbamate|CS-0041621

Structure of 147611-03-8

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General Information

  • CAS No. 147611-03-8
  • Cat. No. CS-0041621
  • Purity ≥98%
  • MDL No. MFCD12198553
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₃H₂₄N₂O₂
  • Molecular Weight 240.35
  • Synonym(s) None
  • SMILES O=C(OC(C)(C)C)NC1CC2(CCNCC2)C1

Description

tert-Butyl (7-azaspiro[3.5]nonan-2-yl)carbamate features a rigid spirocyclic core that imparts conformational stability, enabling precise stereochemical control in synthetic sequences. The carbamate group offers robust protection for amine functionalities under standard conditions, facilitating efficient incorporation into complex molecular architectures.

Application

tert-Butyl (7-azaspiro[3.5]nonan-2-yl)carbamate serves as a versatile, bench-stable building block for the synthesis of spirocyclic amines in medicinal chemistry. The carbamate group enables selective deprotection under mild acidic conditions, while the rigid 7-azaspiro[3.5]nonane core provides conformational constraint ideal for target-oriented synthesis. It functions effectively in standard coupling reactions and tolerates a range of functional groups, facilitating efficient access to complex heterocyclic scaffolds.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   50.36
  • LogP   2.0433
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   1

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