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CS-W001157 4
Total: USD 88.00

Boc-(7-Azaspiro[3.5]nonane)-NH2

  • CAS No. 1239319-82-4

  • Cat. No. CS-0041620
  • Molecule weight240.35
  • Purity≥95%
  • MDL No.MFCD14581153

*For research and further manufacturing use only, not for direct human use.

Boc-(7-Azaspiro[3.5]nonane)-NH2|CS-0041620

Structure of 1239319-82-4

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General Information

  • CAS No. 1239319-82-4
  • Cat. No. CS-0041620
  • Purity ≥95%
  • MDL No. MFCD14581153
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₃H₂₄N₂O₂
  • Molecular Weight 240.35
  • Synonym(s) None
  • SMILES O=C(OC(C)(C)C)N1CCC2(CC1)CC(N)C2

Description

tert-Butyl 2-amino-7-azaspiro[3.5]nonane-7-carboxylate features a rigid spirocyclic scaffold with a primary amine and protected carboxylic acid, enabling direct incorporation into complex heterocycles. This bench-stable, moisture-tolerant building block supports efficient access to bioactive alkaloids and pharmaceutical intermediates through straightforward deprotection and functionalization.

Application

tert-Butyl 2-amino-7-azaspiro[3.5]nonane-7-carboxylate serves as a versatile spirocyclic scaffold for medicinal chemistry, enabling efficient access to constrained nitrogen-containing heterocycles. The protected amine and carboxylate groups offer orthogonal functionality, facilitating modular derivatization via standard coupling, reductive amination, or cyclization protocols. Bench-stable and readily purified, it supports scalable synthesis of bioactive molecules and API intermediates.

Synthesis

  • Route1
    • null|null
      1239320-24-1
    • ~%
    • In-stock
      Boc-(7-Azaspiro[3.5]nonane)-NH2|CS-0041620
      1239319-82-4

    References

    • US2011/319381 A1, ; Page/Page column 19 ;
  • Route2

    References

    • US2011/319381 A1, ; Page/Page column 7 ;
  • Route3

    References

    • US2011/319381 A1, ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   55.56
  • LogP   2.1248
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   0

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