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Structure of 14736-49-3
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This acetic acid derivative features a methoxycarbonyl-substituted phenyl ring, offering enhanced solubility and stability in synthetic transformations. The ortho-positioned ester group enables selective derivatization while maintaining structural integrity under standard bench conditions. Ideal for coupling reactions in medicinal chemistry and polymer synthesis.
2-(2-(Methoxycarbonyl)phenyl)acetic acid serves as a versatile building block for synthesizing biaryl and heterocyclic scaffolds common in medicinal chemistry. Its ortho-carboxylate functionality enables direct coupling reactions, while the pendant carboxylic acid facilitates derivatization via esterification, amidation, or cyclization. The molecule exhibits good bench stability and is readily purified by recrystallization or silica gel chromatography, making it well-suited for reproducible scale-up in API intermediate synthesis.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: