Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

2-Fluoro-5-bromobenzoic acid

  • CAS No. 146328-85-0

  • Cat. No. CS-W008695
  • Purity≥97%
  • MDL No.MFCD00143423

*For research and further manufacturing use only, not for direct human use.

2-Fluoro-5-bromobenzoic acid|CS-W008695

Structure of 146328-85-0

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 146328-85-0
  • Cat. No. CS-W008695
  • Purity ≥97%
  • MDL No. MFCD00143423
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₄BrFO₂
  • Molecular Weight 219.01
  • Synonym(s) BUTTPARK 19\01-67
  • SMILES BrC1=CC=C(F)C(C(O)=O)=C1

Description

cis-4-Hydroxy-L-proline (CHP) is a proline analog that inhibits collagen synthesis and has been used as an anticancer compound. CHP blocked myotube formation and expression of sarcomeric myosin heavy chain in C2C12 murine skeletal muscle cells. CHP inhibited proliferation of murine Panc02 pancreatic carcinoma cell line3 and rat pancreatic carcinoma cell line DSL6A. cis-4-Hydroxy-L-proline and other hydrosyl-L-prolines are important intermediates for chiral synthesis of potential drugs.

Synthesis

  • Route1

    References

    • Li, Qun; Woods, Keith W.; Zhu, Gui-Dong; Fischer, John P.; Gong, Jianchun; Li, Tongmei; Gandhi, Virajkumar; Thomas, Sheela A.; Packard, Garrick K.; Song, Xiaohong; Abrams, Jason N.; Diebold, Robert B.; Dinges, Jurgen; Hutchins, Charles W.; Stoll, Vincent S.; Rosenberg, Saul H.; Giranda, Vincent L. Patent: US2003/199511 A1, 2003 ; Location in patent: Page/Page column 39 ;
  • Route2
    • null|null
      124-38-9
    • null|null
      460-00-4
    • ~83%
    • In-stock
      2-Fluoro-5-bromobenzoic acid|CS-W008695
      146328-85-0

    References

    • Onda, Kenichi; Shiraki, Ryota; Ogiyama, Takashi; Yokoyama, Kazuhiro; Momose, Kazuhiro; Katayama, Naoko; Orita, Masaya; Yamaguchi, Tomohiko; Furutani, Masako; Hamada, Noritaka; Takeuchi, Makoto; Okada, Minoru; Ohta, Mitsuaki; Tsukamoto, Shin-ichi Bioorganic and Medicinal Chemistry, 2008 , vol. 16, # 23 p. 10001 - 10012
  • Route3

    References

    • Sedinkin, Sergey L.; Rath, Nigam P.; Bauer, Eike B. Journal of Organometallic Chemistry, 2008 , vol. 693, # 18 p. 3081 - 3091

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS06
Signal Word : Danger
UN#: 2811
Class : 6.1
Packing Group : Ⅲ
Hazard Statements : H301
Precautionary Statements : P264-P270-P330-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   37.3
  • LogP   2.2864
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   1

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 2-Fluoro-5-bromobenzoic acid sigma2-Fluoro-5-bromobenzoic acid manufacturer2-Fluoro-5-bromobenzoic acid price2-Fluoro-5-bromobenzoic acid structure2-Fluoro-5-bromobenzoic acid SDSbuy 2-Fluoro-5-bromobenzoic acid2-Fluoro-5-bromobenzoic acid supplier2-Fluoro-5-bromobenzoic acid uses2-Fluoro-5-bromobenzoic acid molecular weightprice of 2-Fluoro-5-bromobenzoic acid2-Fluoro-5-bromobenzoic acid chemical name formula of 2-Fluoro-5-bromobenzoic acid
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label