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Structure of 40851-95-4
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6-Chloropyridine-2,3-diamine features a pyridine core with strategically positioned chlorine and diamine functionalities, enabling direct incorporation into heterocyclic scaffolds. The ortho-diamine motif facilitates metal coordination and coupling reactions, while the chloro substituent offers a handle for nucleophilic substitution or cross-coupling transformations under standard conditions. This bench-stable compound serves as a key intermediate in the synthesis of bioactive nitrogen-rich architectures.
6-Chloropyridine-2,3-diamine serves as a versatile building block in medicinal chemistry, enabling the construction of bioactive heterocycles through palladium-catalyzed cross-coupling and nucleophilic substitution reactions. Its ortho-diamine functionality offers enhanced reactivity for metal-directed functionalization, while the chlorine substituent provides a reliable handle for late-stage diversification. The compound exhibits good bench stability and facilitates straightforward purification, making it well-suited for iterative synthesis campaigns in API development.
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GHS Pictogram :
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GHS No : GHS07,GHS08
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Signal Word : Danger
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H317-H319-H334-H335
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Precautionary Statements : P261-P264-P270-P271-P272-P280-P284-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: