H-DL-Glu(Ome)-OH

Name: H-DL-Glu(Ome)-OH
Brand: ChemScene
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CAS No. 14487-45-7
Cat. No. CS-0150702
Purity≥95%
MDL No.MFCD00063110

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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General Information

CAS No. 14487-45-7
Cat. No. CS-0150702
Purity ≥95%
MDL No. MFCD00063110
Storage 4°C, protect from light
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₆H₁₁NO₄
Molecular Weight 161.16
Synonym(s) None
SMILES COC(=O)CCC(C(=O)O)N

Description

H-DL-Glu(Ome)-OH features a protected glutamic acid residue with a methyl ester group, enabling stable incorporation into peptide synthesis workflows. This derivative delivers enhanced solubility and handling convenience, facilitating efficient coupling reactions under standard conditions.

Application

H-DL-Glu(Ome)-OH serves as a versatile building block for peptide synthesis, enabling the introduction of a hydrophilic, ionizable glutamic acid side chain with orthogonal protection. The methyl ester group provides stability during coupling steps and facilitates selective deprotection under mild conditions, while the free α-carboxyl and α-amino functionalities support standard amide bond formation. Its balanced solubility and compatibility with common coupling reagents make it ideal for both solid-phase and solution-phase synthesis workflows.

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

TPSA 89.62
LogP -0.6485
H_Acceptors 4
H_Donors 2
Rotatable_Bonds 4

Other Classifications

Bioactive Molecules Peptides

Life Science Amino Acids and their Derivatives Glutamic acid and derivatives

Building Blocks Functional Group Ester

Chemical Biology Peptide Chemistry Unnatural Amino Acid Derivatives

Key Words

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H-DL-Glu(Ome)-OH

CAS No. 14487-45-7

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