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CS-W001157 4
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Benzyl 3-Hydroxypropionate

  • CAS No. 14464-10-9

  • Cat. No. CS-0156247
  • Purity≥97%
  • MDL No.MFCD00029657

*For research and further manufacturing use only, not for direct human use.

Benzyl 3-Hydroxypropionate|CS-0156247

Structure of 14464-10-9

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General Information

  • CAS No. 14464-10-9
  • Cat. No. CS-0156247
  • Purity ≥97%
  • MDL No. MFCD00029657
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₁₂O₃
  • Molecular Weight 180.20
  • Synonym(s) None
  • SMILES C1=CC=C(C=C1)COC(=O)CCO

Description

Benzyl 3-hydroxypropionate features a hydroxyl group flanked by ester and alkyl functionalities, enabling selective derivatization in synthetic sequences. This bench-stable compound integrates readily into complex molecular architectures, offering enhanced solubility in organic solvents and compatibility with standard coupling conditions.

Application

Benzyl 3-hydroxypropionate serves as a versatile synthetic intermediate for the construction of γ-hydroxy esters and related bioactive scaffolds. Its pendant hydroxyl group enables selective protection, oxidation, or derivatization, while the benzyl ester facilitates mild deprotection under hydrogenolysis conditions. The molecule exhibits good bench stability and is compatible with standard organic transformations, making it valuable in medicinal chemistry and process development workflows.

Synthesis

  • Route1

    References

    • Chemical and pharmaceutical bulletin, , vol. 20, # 8 p. 1612 - 1616

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   46.53
  • LogP   1.1122
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   4

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