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CS-W001157 4
Total: USD 88.00

1-(Fluoromethyl)cyclopropanamine Hydrochloride

  • CAS No. 1445951-06-3

  • Cat. No. CS-0139594
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

1-(Fluoromethyl)cyclopropanamine Hydrochloride|CS-0139594

Structure of 1445951-06-3

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General Information

  • CAS No. 1445951-06-3
  • Cat. No. CS-0139594
  • Purity ≥97%
  • MDL No. None
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄H₉ClFN
  • Molecular Weight 125.57
  • Synonym(s) None
  • SMILES NC1(CF)CC1.Cl

Description

1-(Fluoromethyl)cyclopropanamine Hydrochloride delivers a unique fluorinated cyclopropyl scaffold with enhanced metabolic stability and membrane permeability. This bench-stable, moisture-tolerant amine integrates readily into bioactive molecule design, offering precise spatial orientation for target engagement in medicinal chemistry applications.

Application

1-(Fluoromethyl)cyclopropanamine Hydrochloride serves as a versatile building block for medicinal chemistry, enabling the incorporation of a fluorinated alkylcyclopropane motif with enhanced metabolic stability. The amine functionality facilitates straightforward derivatization via amidation, alkylation, or reductive amination, while the hydrochloride salt ensures excellent bench stability and ease of handling. Its compatibility with standard coupling conditions makes it a practical choice for constructing bioactive scaffolds in drug discovery campaigns.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   26.02
  • LogP   0.869
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   1

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