(S-Piperidin-3-yl)methanol

Name: (S-Piperidin-3-yl)methanol
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CAS No. 144539-77-5
Cat. No. CS-W019674
Purity≥95%
MDL No.MFCD10567175

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General Information

CAS No. 144539-77-5
Cat. No. CS-W019674
Purity ≥95%
MDL No. MFCD10567175
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₆H₁₃NO
Molecular Weight 115.17
Synonym(s) (S)-Piperidin-3-ylmethanol
SMILES OC[C@@H]1CNCCC1

Description

(S-Piperidin-3-yl)methanol features a chiral piperidine core with a primary alcohol handle, enabling direct functionalization in asymmetric synthesis. This bench-stable scaffold integrates readily into bioactive molecule frameworks, offering a polar, nitrogen-rich site for derivatization under standard conditions.

Application

(S)-Piperidin-3-yl)methanol serves as a versatile chiral building block in medicinal chemistry, enabling efficient access to piperidine-containing scaffolds common in bioactive molecules. Its primary alcohol functionality facilitates straightforward derivatization via esterification, etherification, and coupling reactions. The molecule exhibits good bench stability and compatibility with standard protecting group strategies, making it well-suited for multi-step synthesis and process development workflows.

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

TPSA 32.26
LogP -0.0217
H_Acceptors 2
H_Donors 2
Rotatable_Bonds 1

Other Classifications

Building Blocks Skeleton Chiral compounds Chiral Building Blocks

Building Blocks Skeleton Aliphatic heterocycle compounds Piperidine compounds

Key Words

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(S-Piperidin-3-yl)methanol

CAS No. 144539-77-5

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