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CS-W001157 4
Total: USD 88.00

(R)-Piperidin-3-ol

  • CAS No. 62414-68-0

  • Cat. No. CS-0053770
  • Purity≥96%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

(R)-Piperidin-3-ol|CS-0053770

Structure of 62414-68-0

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General Information

  • CAS No. 62414-68-0
  • Cat. No. CS-0053770
  • Purity ≥96%
  • MDL No. None
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₁₁NO
  • Molecular Weight 101.15
  • Synonym(s) (R)-3-Piperidinol
  • SMILES O[C@@H]1CCCNC1

Description

(R)-Piperidin-3-ol is a chiral building block featuring a hydroxyl group at the 3-position of a piperidine ring, enabling selective functionalization in asymmetric synthesis. This bench-stable, moisture-tolerant scaffold integrates readily into bioactive molecules and pharmaceutical intermediates.

Application

(R)-Piperidin-3-ol serves as a key chiral building block in medicinal chemistry, enabling the construction of bioactive heterocycles and pharmaceutical intermediates. Its well-defined stereochemistry facilitates predictable reactivity in functional group transformations and coupling reactions. The molecule exhibits good bench stability and compatibility with standard synthetic protocols, supporting efficient incorporation into complex molecular architectures.

Synthesis

  • Route1

    References

    • Kovackova, Sona; Dracinsky, Martin; Rejman, Dominik Tetrahedron, 2011 , vol. 67, # 7 p. 1485 - 1500
  • Route2
    • null|null
      804500-80-9
    • ~94%
    • In-stock
      (R)-Piperidin-3-ol|CS-0053770
      62414-68-0

    References

    • Grishina; Veselov; Davankov; Il'in; Zefirov Russian Journal of Organic Chemistry, 2008 , vol. 44, # 2 p. 282 - 287
  • Route3
    • (R)-5-Hydroxypiperidin-2-one|CS-D0041
      102774-92-5
    • ~60%
    • In-stock
      (R)-Piperidin-3-ol|CS-0053770
      62414-68-0

    References

    • Huh, Nam; Thompson, Charles M. Tetrahedron, 1995 , vol. 51, # 21 p. 5935 - 5950

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05
Signal Word : Danger
UN#: 3263
Class : 8
Packing Group : Ⅱ
Hazard Statements : H314
Precautionary Statements : P260-P264-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P363-P405-P501

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Computational Chemistry Data

  • TPSA   32.26
  • LogP   -0.2693
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   0

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