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Structure of 144294-43-9
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5-Methylpyridazin-3-amine is a nitrogen-rich heterocyclic scaffold featuring a methyl-substituted pyridazine core and a primary amine at the 3-position. This electron-donating amine group enhances reactivity in coupling processes, while the methyl moiety improves metabolic stability and lipophilicity. The compound serves as a key building block in medicinal chemistry, particularly for kinase inhibitors and targeted therapeutics. Its bench-stable nature facilitates handling under standard conditions.
5-Methylpyridazin-3-amine serves as a versatile heterocyclic building block in medicinal chemistry, enabling efficient access to bioactive scaffolds. Its pyridazinamine core exhibits favorable reactivity in Suzuki-Miyaura and Buchwald-Hartwig couplings, while the methyl group enhances metabolic stability. The compound demonstrates excellent bench stability and compatibility with common protecting group strategies, facilitating straightforward purification and integration into multi-step synthesis workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: