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Structure of 1314978-36-3
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5-Chloropyridazin-3-amine features a chlorinated pyridazinone core with a primary amine at the 3-position, enabling direct coupling in heterocyclic synthesis. The electron-deficient ring system facilitates nucleophilic substitution, while the amine group serves as a handle for derivatization. This bench-stable compound integrates readily into medicinal chemistry campaigns targeting kinase inhibitors and agrochemical scaffolds.
5-Chloropyridazin-3-amine serves as a versatile building block in medicinal chemistry, enabling efficient construction of heterocyclic scaffolds via nucleophilic substitution and cross-coupling reactions. Its chlorine atom at the 5-position offers high reactivity toward amines, thiols, and boronic acids, facilitating rapid diversification. The compound exhibits excellent bench stability and ease of purification, making it well-suited for scalable synthesis and API intermediate development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P280-P302+P352
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Lot numbers can be found on the outside label of a product: