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CS-W001157 4
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5-Chloropyridazin-3-amine

  • CAS No. 1314978-36-3

  • Cat. No. CS-0050510
  • Molecule weight129.55
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

5-Chloropyridazin-3-amine|CS-0050510

Structure of 1314978-36-3

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General Information

  • CAS No. 1314978-36-3
  • Cat. No. CS-0050510
  • Purity ≥97%
  • MDL No. None
  • Storage -20°C, sealed storage, away from moisture and light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄H₄ClN₃
  • Molecular Weight 129.55
  • Synonym(s) 5-chloro-3-Pyridazinamine
  • SMILES NC1=NN=CC(Cl)=C1

Description

5-Chloropyridazin-3-amine features a chlorinated pyridazinone core with a primary amine at the 3-position, enabling direct coupling in heterocyclic synthesis. The electron-deficient ring system facilitates nucleophilic substitution, while the amine group serves as a handle for derivatization. This bench-stable compound integrates readily into medicinal chemistry campaigns targeting kinase inhibitors and agrochemical scaffolds.

Application

5-Chloropyridazin-3-amine serves as a versatile building block in medicinal chemistry, enabling efficient construction of heterocyclic scaffolds via nucleophilic substitution and cross-coupling reactions. Its chlorine atom at the 5-position offers high reactivity toward amines, thiols, and boronic acids, facilitating rapid diversification. The compound exhibits excellent bench stability and ease of purification, making it well-suited for scalable synthesis and API intermediate development.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P280-P302+P352

Quality Control

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Computational Chemistry Data

  • TPSA   51.8
  • LogP   0.7122
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   0

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