Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

VT00065

  • CAS No. 144163-68-8

  • Cat. No. CS-0199923
  • Purity≥98%
  • MDL No.MFCD02854205

*For research and further manufacturing use only, not for direct human use.

VT00065|CS-0199923

Structure of 144163-68-8

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 144163-68-8
  • Cat. No. CS-0199923
  • Purity ≥98%
  • MDL No. MFCD02854205
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₈N₂S
  • Molecular Weight 128.20
  • Synonym(s) None
  • SMILES CNCC1=NC=CS1

Description

N-Methyl-1-(thiazol-2-yl)methanamine features a thiazole ring linked to a methylated amine group, delivering enhanced solubility and stability. This scaffold integrates readily into medicinal chemistry libraries, serving as a key building block for bioactive molecules with improved metabolic resilience and targeted pharmacophore engagement.

Application

N-Methyl-1-(thiazol-2-yl)methanamine serves as a versatile building block in medicinal chemistry, enabling efficient access to thiazole-containing scaffolds prevalent in bioactive molecules. Its amine functionality facilitates straightforward derivatization via alkylation, acylation, or coupling reactions, while the thiazole ring provides metabolic stability and favorable pharmacophoric properties. The compound exhibits good bench stability and is compatible with standard purification methods, making it well-suited for parallel synthesis campaigns and API intermediate development.

Synthesis

  • Route1
    • In-stock
      2-Formylthiazole|CS-W002420
      10200-59-6
    • null|null
      593-51-1
    • ~18%
    • In-stock
      VT00065|CS-0199923
      144163-68-8

    References

    • Kempf, Dale J.; Codacovi, Lynnmarie; Wang, Xiu Chun; Kohlbrenner, William E.; Wideburg, Norman E.; et al. Journal of Medicinal Chemistry, 1993 , vol. 36, # 3 p. 320 - 330

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302
Precautionary Statements : P264-P270-P330-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   24.92
  • LogP   0.8625
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   2

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • VT00065 sigmaVT00065 manufacturerVT00065 priceVT00065 structureVT00065 SDSbuy VT00065VT00065 supplierVT00065 usesVT00065 molecular weightprice of VT00065VT00065 chemical name formula of VT00065
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label