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Structure of 143612-79-7
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3-(4-chlorobutyl)-1H-indole-5-carbonitrile features a reactive chloroalkyl tether appended to the indole core, enabling site-specific conjugation in bioconjugation and medicinal chemistry. The para-cyano group enhances electronic withdrawal, while the aliphatic chain offers flexible spacing. This compound serves as a modular building block for targeted probe development and functional material synthesis under standard conditions.
3-(4-Chlorobutyl)-1H-indole-5-carbonitrile serves as a versatile building block for indole-based heterocycles, enabling efficient functionalization via nucleophilic substitution. The pendant chloroalkyl chain facilitates facile conjugation with amines, thiols, and other nucleophiles, while the nitrile group provides compatibility with standard transformations including hydrolysis or reductive amination. Its bench-stable nature and straightforward purification make it well-suited for medicinal chemistry campaigns and API intermediate synthesis.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: