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CS-W001157 4
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2-Bromo-5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine Edoxaban Impurity

  • CAS No. 143150-92-9

  • Cat. No. CS-0229428
  • Purity≥98%
  • MDL No.MFCD22035142

*For research and further manufacturing use only, not for direct human use.

2-Bromo-5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine Edoxaban  Impurity|CS-0229428

Structure of 143150-92-9

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General Information

  • CAS No. 143150-92-9
  • Cat. No. CS-0229428
  • Purity ≥98%
  • MDL No. MFCD22035142
  • Storage Sealed in dry,2-8℃
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₉BrN₂S
  • Molecular Weight 233.13
  • Synonym(s) Thiazolo[5,4-c]pyridine, 2-bromo-4,5,6,7-tetrahydro-5-methyl-
  • SMILES CN1CCC2=C(SC(Br)=N2)C1

Synthesis

  • Route1

    References

    • DAIICHI SANKYO COMPANY, LIMITED; Kawanami, Koutarou Patent: US2013/144061 A1, 2013 ; Location in patent: Paragraph 0248; 0249; 0250 ;
  • Route2
    • null|null
      50-00-0
    • 2-Bromo-4,5,6,7-tetrahydro-[1,3]thiazolo[5,4-c]pyridine|CS-0060817
      365996-07-2
    • ~%
    • 2-Bromo-5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine Edoxaban  Impurity|CS-0229428
      143150-92-9

    References

    • Haginoya, Noriyasu; Komoriya, Satoshi; Osanai, Ken; Yoshino, Toshiharu; Nagata, Tsutomu; Nagamochi, Masatoshi; Muto, Ryo; Yamaguchi, Mitsuhiro; Nagahara, Takayasu; Kanno, Hideyuki Heterocycles, 2004 , vol. 63, # 7 p. 1555 - 1561
  • Route3
    • null|null
      79099-07-3
    • ~%
    • 2-Bromo-5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine Edoxaban  Impurity|CS-0229428
      143150-92-9

    References

    • Haginoya, Noriyasu; Komoriya, Satoshi; Osanai, Ken; Yoshino, Toshiharu; Nagata, Tsutomu; Nagamochi, Masatoshi; Muto, Ryo; Yamaguchi, Mitsuhiro; Nagahara, Takayasu; Kanno, Hideyuki Heterocycles, 2004 , vol. 63, # 7 p. 1555 - 1561

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   16.13
  • LogP   1.8935
  • H_Acceptors   3
  • H_Donors   0
  • Rotatable_Bonds   0

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