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CS-W001157 4
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3-Bromo-5-hydrazinylpyridine dihydrochloride

  • CAS No. 1427195-27-4

  • Cat. No. CS-0214897
  • Molecule weight260.95
  • Purity≥98%
  • MDL No.MFCD24368624

*For research and further manufacturing use only, not for direct human use.

3-Bromo-5-hydrazinylpyridine dihydrochloride|CS-0214897

Structure of 1427195-27-4

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General Information

  • CAS No. 1427195-27-4
  • Cat. No. CS-0214897
  • Purity ≥98%
  • MDL No. MFCD24368624
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₈BrCl₂N₃
  • Molecular Weight 260.95
  • Synonym(s) None
  • SMILES NNC1=CN=CC(Br)=C1.Cl.Cl

Description

3-Bromo-5-hydrazinylpyridine dihydrochloride features a pyridine core functionalized with a bromo group at the 3-position and a hydrazinyl moiety at the 5-position, delivering a reactive handle for cross-coupling and bioconjugation. This bench-stable salt form enhances solubility and handling in aqueous reaction media.

Application

3-Bromo-5-hydrazinylpyridine dihydrochloride serves as a versatile building block for constructing pyridine-based heterocycles, enabling efficient C–N and C–C coupling reactions. The hydrazinyl group facilitates palladium-catalyzed cross-coupling and cyclization processes, while the bromo substituent supports further functionalization via standard transition-metal-mediated transformations. Bench-stable and readily purified, it functions effectively in medicinal chemistry and materials synthesis workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   50.94
  • LogP   1.9733
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   1

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