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Structure of 141943-04-6
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1-Benzylpiperidine-3-carboxylic acid features a rigid, electron-rich piperidine core functionalized with a benzyl group and a carboxylic acid at the 3-position. This combination enables direct integration into bioactive scaffolds, particularly in CNS-targeted pharmaceuticals, where the polar carboxylate enhances solubility and metabolic stability under standard conditions.
1-Benzylpiperidine-3-carboxylic acid serves as a versatile scaffold for medicinal chemistry, enabling the construction of bioactive heterocycles through standard coupling and functionalization reactions. Its benzylic piperidine core offers enhanced metabolic stability and favorable physicochemical properties. The carboxylic acid group facilitates amide bond formation, esterification, and derivatization under mild conditions, supporting efficient synthesis of peptide-like compounds and drug candidates. Bench-stable and readily purified by recrystallization or chromatography, it functions effectively in both small-scale exploratory studies and process development workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: