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(S)-Methyl morpholine-2-carboxylate hydrochloride

  • CAS No. 1417789-45-7

  • Cat. No. CS-0042560
  • Molecule weight181.62
  • Purity≥95%
  • MDL No.MFCD21648490

*For research and further manufacturing use only, not for direct human use.

(S)-Methyl morpholine-2-carboxylate hydrochloride|CS-0042560

Structure of 1417789-45-7

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General Information

  • CAS No. 1417789-45-7
  • Cat. No. CS-0042560
  • Purity ≥95%
  • MDL No. MFCD21648490
  • Storage RT, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₁₂ClNO₃
  • Molecular Weight 181.62
  • Synonym(s) methyl (2S)-morpholine-2-carboxylate,hydrochloride
  • SMILES O=C([C@@H]1CNCCO1)OC.[H]Cl

Description

(S)-Methyl morpholine-2-carboxylate hydrochloride is a chiral building block featuring a stereodefined morpholine core and a carboxylate ester group. This bench-stable salt delivers high enantioselectivity in asymmetric synthesis, enabling efficient access to bioactive alkaloids and pharmaceutical intermediates through controlled functionalization at the 2-position.

Application

(S)-Methyl morpholine-2-carboxylate hydrochloride serves as a chiral building block for medicinal chemistry and catalytic synthesis, enabling stereoselective transformations through its well-defined enantiomeric purity. The morpholine scaffold provides enhanced solubility and metabolic stability, while the carboxylate functionality supports efficient derivatization via amide coupling or esterification. Bench-stable and readily purified by crystallization, it functions reliably in standard peptide and heterocycle synthesis workflows.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   47.56
  • LogP   -0.4304
  • H_Acceptors   4
  • H_Donors   1
  • Rotatable_Bonds   1

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