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Methyl (R)-morpholine-2-carboxylate hydrochloride

  • CAS No. 1352709-55-7

  • Cat. No. CS-0103649
  • Molecule weight181.62
  • Purity≥97%
  • MDL No.MFCD21606371

*For research and further manufacturing use only, not for direct human use.

Methyl (R)-morpholine-2-carboxylate hydrochloride|CS-0103649

Structure of 1352709-55-7

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General Information

  • CAS No. 1352709-55-7
  • Cat. No. CS-0103649
  • Purity ≥97%
  • MDL No. MFCD21606371
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₁₂ClNO₃
  • Molecular Weight 181.62
  • Synonym(s) (R)-methyl morpholine-2-carboxylate hydrochloride
  • SMILES O=C([C@H]1CNCCO1)OC.[H]Cl

Description

Methyl (R)-morpholine-2-carboxylate hydrochloride is a chiral building block featuring a stereochemically defined morpholine ring and a carboxylate ester. This bench-stable, moisture-tolerant salt facilitates asymmetric synthesis in medicinal chemistry, enabling efficient access to enantiopure scaffolds through selective derivatization or catalytic transformation.

Application

Methyl (R)-morpholine-2-carboxylate hydrochloride serves as a chiral building block for synthesizing bioactive molecules, leveraging the morpholine ring’s metabolic stability and hydrogen-bonding capacity. The carboxylate ester enables direct functionalization in coupling reactions, while the hydrochloride salt enhances crystallinity and handling. Its stereochemical purity supports enantioselective synthesis, facilitating efficient access to pharmaceutical intermediates through established transformations.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   47.56
  • LogP   -0.4304
  • H_Acceptors   4
  • H_Donors   1
  • Rotatable_Bonds   1

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