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CS-W001157 4
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2-(Hydroxymethyl)pyridin-3-ol hydrochloride

  • CAS No. 14173-30-9

  • Cat. No. CS-0020046
  • Purity≥97%
  • MDL No.MFCD00006349

*For research and further manufacturing use only, not for direct human use.

2-(Hydroxymethyl)pyridin-3-ol hydrochloride|CS-0020046

Structure of 14173-30-9

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General Information

  • CAS No. 14173-30-9
  • Cat. No. CS-0020046
  • Purity ≥97%
  • MDL No. MFCD00006349
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₈ClNO₂
  • Molecular Weight 161.59
  • Synonym(s) pyridin-2-ylmethanol hydrochloride
  • SMILES OCC1=NC=CC=C1O.[H]Cl

Description

This hydrochloride salt features a pyridin-3-ol core with a hydroxymethyl group at the 2-position, delivering enhanced solubility and stability under standard conditions. The protonated nitrogen improves handling in aqueous reaction systems, while the phenolic OH enables hydrogen bonding and coordination. Ideal for medicinal chemistry scaffolds requiring balanced polarity and reactivity.

Application

2-(Hydroxymethyl)pyridin-3-ol hydrochloride serves as a versatile building block in medicinal chemistry, enabling efficient functionalization at the pyridine ring and hydroxymethyl side chain. Its dual functionality supports diverse transformations, including Suzuki-Miyaura coupling and derivatization of the phenolic OH. The hydrochloride salt enhances solubility and bench stability, facilitating handling and purification in standard synthetic workflows.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   53.35
  • LogP   0.7013
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   1

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