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CS-W001157 4
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Ethyl 8-oxo-1,4-dioxaspiro[4.5]Decane-7-carboxylate

  • CAS No. 14160-65-7

  • Cat. No. CS-0446220
  • Molecule weight228.24
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

Ethyl 8-oxo-1,4-dioxaspiro[4.5]Decane-7-carboxylate|CS-0446220

Structure of 14160-65-7

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General Information

  • CAS No. 14160-65-7
  • Cat. No. CS-0446220
  • Purity ≥98%
  • MDL No. None
  • Storage Sealed in dry,2-8℃
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₁₆O₅
  • Molecular Weight 228.24
  • Synonym(s) 8-oxo-1,4-dioxaspiro[4.5]decane-7-carboxylic acid ethyl ester
  • SMILES CCOC(=O)C1CC2(CCC1=O)OCCO2

Synthesis

  • Route1

    References

    • Carter, Percy H. Patent: US2005/277666 A1, 2005 ; Location in patent: Page/Page column 4-5 ;
  • Route2
    • null|null
      19719-88-1
    • ~85%
    • Ethyl 8-oxo-1,4-dioxaspiro[4.5]Decane-7-carboxylate|CS-0446220
      14160-65-7

    References

    • Tsuda; Yoshimoto; Yamashita; Kaneda Chemical and Pharmaceutical Bulletin, 1981 , vol. 29, # 11 p. 3238 - 3248
  • Route3

    References

    • Cherney, Robert J.; Mo, Ruowei; Meyer, Dayton T.; Voss, Matthew E.; Yang, Michael G.; Santella III, Joseph B.; Duncia, John V.; Lo, Yvonne C.; Yang, Gengjie; Miller, Persymphonie B.; Scherle, Peggy A.; Zhao, Qihong; Mandlekar, Sandhya; Cvijic, Mary Ellen; Barrish, Joel C.; Decicco, Carl P.; Carter, Percy H. Bioorganic and Medicinal Chemistry Letters, 2010 , vol. 20, # 8 p. 2425 - 2430

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   61.83
  • LogP   0.6618
  • H_Acceptors   5
  • H_Donors   0
  • Rotatable_Bonds   2

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