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CS-W001157 4
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2-Fluoro-6-methoxypyridin-3-ylboronic acid

  • CAS No. 1402238-30-5

  • Cat. No. CS-0037031
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

2-Fluoro-6-methoxypyridin-3-ylboronic acid|CS-0037031

Structure of 1402238-30-5

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General Information

  • CAS No. 1402238-30-5
  • Cat. No. CS-0037031
  • Purity ≥98%
  • MDL No. None
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₇BFNO₃
  • Molecular Weight 170.93
  • Synonym(s) 2-Fluoro-6-methoxypyridine-3-boronic acid
  • SMILES COC1=CC=C(B(O)O)C(F)=N1

Description

2-Fluoro-6-methoxypyridin-3-ylboronic acid features a pyridine core functionalized with fluorine and methoxy groups, enabling enhanced electronic tuning and metabolic stability. This bench-stable boronic acid integrates readily into Suzuki-Miyaura couplings, delivering efficient access to substituted heterocycles in medicinal chemistry and materials synthesis.

Application

2-Fluoro-6-methoxypyridin-3-ylboronic acid serves as a versatile building block in Suzuki-Miyaura cross-coupling reactions, enabling efficient C–C bond formation under mild conditions. The ortho-fluoro and meta-methoxy substituents provide enhanced stability and predictable reactivity, while the boronic acid group offers excellent functional group tolerance and ease of purification. Its bench-stable nature and compatibility with diverse reaction partners make it a practical choice for constructing substituted pyridine scaffolds in medicinal chemistry and materials science applications.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362-P405-P501

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Computational Chemistry Data

  • TPSA   62.58
  • LogP   -1.0909
  • H_Acceptors   4
  • H_Donors   2
  • Rotatable_Bonds   2

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