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CS-W001157 4
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(6-Fluoro-2-methoxypyridin-3-yl)boronic acid

  • CAS No. 1443380-14-0

  • Cat. No. CS-0435819
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

(6-Fluoro-2-methoxypyridin-3-yl)boronic acid|CS-0435819

Structure of 1443380-14-0

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General Information

  • CAS No. 1443380-14-0
  • Cat. No. CS-0435819
  • Purity ≥98%
  • MDL No. None
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₇BFNO₃
  • Molecular Weight 170.93
  • Synonym(s) None
  • SMILES COC1=NC(F)=CC=C1B(O)O

Description

This boronate moiety enables direct coupling in Suzuki-Miyaura reactions, offering enhanced reactivity and stability under standard conditions. The fluorinated pyridine scaffold provides favorable electronic tuning, while the methoxy group improves solubility and reduces aggregation during synthesis.

Application

(6-Fluoro-2-methoxypyridin-3-yl)boronic acid serves as a versatile building block in Suzuki-Miyaura coupling reactions, enabling efficient C–C bond formation with aryl and vinyl halides. The fluorine and methoxy groups provide orthogonal reactivity and enhanced stability, while the boronic acid functionality facilitates reliable coupling under mild conditions. Its bench-stable nature and compatibility with diverse functional groups make it ideal for constructing complex heterocyclic scaffolds in medicinal chemistry and materials science applications.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   62.58
  • LogP   -1.0909
  • H_Acceptors   4
  • H_Donors   2
  • Rotatable_Bonds   2

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