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CS-W001157 4
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1-Methyl-4-nitro-3-propyl-1H-pyrazole-5-carboxamide Sildenafil Impurity

  • CAS No. 139756-01-7

  • Cat. No. CS-0166959
  • Purity≥97%
  • MDL No.MFCD02253196

*For research and further manufacturing use only, not for direct human use.

1-Methyl-4-nitro-3-propyl-1H-pyrazole-5-carboxamide  Sildenafil Impurity|CS-0166959

Structure of 139756-01-7

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General Information

  • CAS No. 139756-01-7
  • Cat. No. CS-0166959
  • Purity ≥97%
  • MDL No. MFCD02253196
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₂N₄O₃
  • Molecular Weight 212.21
  • Synonym(s) 5-Carbamoyl-1-methyl-4-nitro-3-propylpyrazole
  • SMILES O=C(C1=C([N+]([O-])=O)C(CCC)=NN1C)N

Synthesis

  • Route1
    • 1-methyl-4-nitro-3-propyl-1H-pyrazole-5-carboxylic acid  Sildenafil Impurity|CS-0166496
      139756-00-6
    • ~94%
    • 1-Methyl-4-nitro-3-propyl-1H-pyrazole-5-carboxamide  Sildenafil Impurity|CS-0166959
      139756-01-7

    References

    • Dale, David J.; Dunn, Peter J.; Golightly, Clare; Hughes, Michael L.; Levett, Philip C.; Pearce, Andrew K.; Searle, Patricia M.; Ward, Gordon; Wood, Albert S. Organic Process Research and Development, 2000 , vol. 4, # 1 p. 17 - 22
  • Route2
    • 1-Methyl-3-propyl-1H-pyrazole-5-carboxylic acid|CS-0006634
      139755-99-0
    • ~%
    • 1-Methyl-4-nitro-3-propyl-1H-pyrazole-5-carboxamide  Sildenafil Impurity|CS-0166959
      139756-01-7

    References

    • Bioorganic and Medicinal Chemistry Letters, , vol. 15, # 17 p. 3900 - 3907
  • Route3

    References

    • Bioorganic and Medicinal Chemistry Letters, , vol. 15, # 17 p. 3900 - 3907

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   104.05
  • LogP   0.3797
  • H_Acceptors   5
  • H_Donors   1
  • Rotatable_Bonds   4

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