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CS-W001157 4
Total: USD 88.00

(4-Bromo-2-(trifluoromethyl)phenyl)boronic acid

  • CAS No. 1394346-22-5

  • Cat. No. CS-0174716
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

(4-Bromo-2-(trifluoromethyl)phenyl)boronic acid|CS-0174716

Structure of 1394346-22-5

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General Information

  • CAS No. 1394346-22-5
  • Cat. No. CS-0174716
  • Purity ≥98%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₅BBrF₃O₂
  • Molecular Weight 268.82
  • Synonym(s) 4-Bromo-2-(trifluoromethyl)benzeneboronic acid
  • SMILES BrC1=CC(C(F)(F)F)=C(B(O)O)C=C1

Description

This boronate moiety features a para-brominated trifluoromethylated aryl group, delivering enhanced stability and compatibility in Suzuki-Miyaura cross-coupling reactions. The electron-deficient ring facilitates efficient palladium-catalyzed bond formation, enabling rapid access to complex heteroaryl architectures under standard conditions.

Application

(4-Bromo-2-(trifluoromethyl)phenyl)boronic acid serves as a versatile building block in palladium-catalyzed cross-coupling reactions, enabling efficient C–C bond formation under standard Suzuki-Miyaura conditions. Its stability, compatibility with diverse functional groups, and predictable reactivity make it ideal for constructing complex aryl scaffolds in medicinal chemistry and materials science applications.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H312-H332
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P363-P501

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Computational Chemistry Data

  • TPSA   40.46
  • LogP   1.1477
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   1

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