(R)-2-(4-Chlorophenyl)piperidine hydrochloride

Name: (R)-2-(4-Chlorophenyl)piperidine hydrochloride
Brand: ChemScene
Availability: InStock
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CAS No. 1391448-39-7
Cat. No. CS-0438620
Purity≥95%
MDL No.None

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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(R)-2-(4-Chlorophenyl)piperidine hydrochloride|CS-0438620

Structure of 1391448-39-7

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Description

(R)-2-(4-Chlorophenyl)piperidine hydrochloride is a chiral piperidine derivative featuring a para-chlorophenyl substituent, offering enhanced metabolic stability and targeted receptor affinity. This bench-stable salt form facilitates handling in synthetic workflows, enabling efficient integration into medicinal chemistry campaigns for CNS-targeted drug discovery.

Application

(R)-2-(4-Chlorophenyl)piperidine hydrochloride serves as a key chiral building block for the synthesis of bioactive molecules, particularly in CNS-targeted therapeutics. Its well-defined stereochemistry and stability under standard reaction conditions enable reliable incorporation into complex scaffolds. The molecule functions effectively in coupling reactions and acts as a versatile intermediate for constructing piperidine-based pharmacophores with demonstrated utility in medicinal chemistry workflows.

General Information

CAS No. 1391448-39-7
Cat. No. CS-0438620
Purity ≥95%
MDL No. None
Storage 4°C, protect from light
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₁₁H₁₅Cl₂N
Molecular Weight 232.15
Synonym(s) (2R)-2-(4-CHLOROPHENYL)PIPERIDINE HYDROCHLORIDE
SMILES ClC1=CC=C([C@H]2CCCCN2)C=C1.Cl

Computational Chemistry Data

TPSA 12.03
LogP 3.5764
H_Acceptors 1
H_Donors 1
Rotatable_Bonds 1

Safety Information

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GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P280-P302+P352

Quality Control

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Other Classifications

Building Blocks Skeleton Aliphatic heterocycle compounds Piperidine compounds

Building Blocks Skeleton Aromatic ring compounds Benzene compounds

Building Blocks Skeleton Chiral compounds Chiral Building Blocks

Key Words

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(R)-2-(4-Chlorophenyl)piperidine hydrochloride

CAS No. 1391448-39-7

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