(S)-1-(6-Methoxypyridin-3-yl)ethanamine hydrochloride

Name: (S)-1-(6-Methoxypyridin-3-yl)ethanamine hydrochloride
Brand: ChemScene
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CAS No. 1391355-13-7
Cat. No. CS-0187941
Purity≥97%
MDL No.None

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
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(S)-1-(6-Methoxypyridin-3-yl)ethanamine hydrochloride|CS-0187941

Structure of 1391355-13-7

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Description

(S)-1-(6-Methoxypyridin-3-yl)ethanamine hydrochloride is a chiral amine featuring a pyridine nitrogen and methoxy group positioned ortho to the ethylamine tether. This bench-stable salt delivers a polar, electron-rich handle for coupling reactions in medicinal chemistry. The stereochemistry at the α-carbon enables selective recognition in asymmetric synthesis, facilitating access to enantioselective drug candidates.

Application

(S)-1-(6-Methoxypyridin-3-yl)ethanamine hydrochloride serves as a valuable chiral building block in medicinal chemistry, enabling the synthesis of pyridine-based bioactive molecules. Its amine functionality facilitates straightforward derivatization via amidation, alkylation, and reductive amination, while the 6-methoxy group enhances solubility and modulates electronic properties. The hydrochloride salt ensures excellent bench stability and ease of handling, supporting scalable applications in API development and fragment-based drug discovery.

General Information

CAS No. 1391355-13-7
Cat. No. CS-0187941
Purity ≥97%
MDL No. None
Storage Store at room temperature, keep dry and cool
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₈H₁₃ClN₂O
Molecular Weight 188.65
Synonym(s) None
SMILES [C@@H](C)(N)C=1C=CC(OC)=NC1.Cl

Computational Chemistry Data

TPSA 48.14
LogP 1.5317
H_Acceptors 3
H_Donors 1
Rotatable_Bonds 2

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Other Classifications

Building Blocks Skeleton Aromatic heterocycle compounds Pyridine compounds

Building Blocks Skeleton Chiral compounds Chiral Building Blocks

Key Words

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(S)-1-(6-Methoxypyridin-3-yl)ethanamine hydrochloride

CAS No. 1391355-13-7

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