O-Phospho-L-threonine

Name: O-Phospho-L-threonine
Brand: ChemScene
Availability: InStock
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CAS No. 1114-81-4
Cat. No. CS-0059358
Purity≥97%
MDL No.MFCD00080958

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Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

Structure of 1114-81-4

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Description

O-Phospho-L-threonine delivers a phosphorylated threonine scaffold ideal for probing kinase activity and signaling pathways. This stable, water-soluble analog features a phosphate group at the hydroxyl position, enabling direct incorporation into peptide substrates or enzymatic assays under physiological conditions.

Application

O-Phospho-L-threonine serves as a key phosphorylated amino acid building block for the synthesis of phosphopeptides and protein kinase substrates. Its stable phosphate ester group enables reliable incorporation into peptide sequences, facilitating studies of post-translational modification. The compound exhibits good bench stability and compatibility with standard solid-phase peptide synthesis protocols, supporting efficient coupling and orthogonal deprotection strategies.

General Information

CAS No. 1114-81-4
Cat. No. CS-0059358
Purity ≥97%
MDL No. MFCD00080958
Storage RT, protect from light
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₄H₁₀NO₆P
Molecular Weight 199.10
Synonym(s) None
SMILES N[C@@H]([C@H](OP(O)(O)=O)C)C(O)=O

Computational Chemistry Data

TPSA 130.08
LogP -1.1039
H_Acceptors 4
H_Donors 4
Rotatable_Bonds 4

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS05
Signal Word : Danger	UN#: 3261
Class : 8	Packing Group : Ⅱ
Hazard Statements : H314
Precautionary Statements : P260-P264-P280-P301+P330+P331-P304+P340-P363-P405-P501

Quality Control

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Other Classifications

Bioactive Molecules Natural Products

Bioactive Molecules Peptides

Life Science Amino Acids and their Derivatives Threonine and derivatives

Chemical Biology Peptide Chemistry Amino Acid Derivatives

Biochemistry Biochemicals and Reagents Amino Acids Biologically-modified Amino Acids

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O-Phospho-L-threonine

CAS No. 1114-81-4

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