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CS-W001157 4
Total: USD 88.00

Tetrazine-Ph-acid

  • CAS No. 1380500-92-4

  • Cat. No. CS-0086631
  • Purity≥96%
  • MDL No.MFCD24503098

*For research and further manufacturing use only, not for direct human use.

Tetrazine-Ph-acid|CS-0086631

Structure of 1380500-92-4

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General Information

  • CAS No. 1380500-92-4
  • Cat. No. CS-0086631
  • Purity ≥96%
  • MDL No. MFCD24503098
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₈N₄O₂
  • Molecular Weight 216.20
  • Synonym(s) None
  • SMILES OC(CC1=CC=C(C2=NN=CN=N2)C=C1)=O

Description

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Application

Tetrazine-Ph-acid serves as a versatile building block for bioorthogonal conjugation and heterocyclic synthesis. Its reactive tetrazine moiety enables efficient inverse electron-demand Diels-Alder (iEDDA) reactions with trans-cyclooctene (TCO) derivatives, facilitating rapid, site-specific labeling under physiological conditions. The phenylacetic acid handle provides orthogonal functionality for further derivatization or purification via standard chromatographic methods. This compound exhibits excellent bench stability and functional group tolerance, making it well-suited for modular synthesis of probes, antibody-drug conjugates, and advanced API intermediates.

Safety Information

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GHS Pictogram :
GHS No : GHS02
Signal Word : Danger
UN#: 3224
Class : 4.1
Packing Group : -
Hazard Statements : H242
Precautionary Statements : P210-P220-P234-P280-P370+P378-P420-P501

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Computational Chemistry Data

  • TPSA   88.86
  • LogP   0.5607
  • H_Acceptors   5
  • H_Donors   1
  • Rotatable_Bonds   3

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