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CS-W001157 4
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Methyltetrazine-amine hydrochloride

  • CAS No. 1596117-29-1

  • Cat. No. CS-0377770
  • Purity≥95%
  • MDL No.MFCD32061909

*For research and further manufacturing use only, not for direct human use.

Methyltetrazine-amine hydrochloride|CS-0377770

Structure of 1596117-29-1

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General Information

  • CAS No. 1596117-29-1
  • Cat. No. CS-0377770
  • Purity ≥95%
  • MDL No. MFCD32061909
  • Storage 4°C, sealed storage, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₁₂ClN₅
  • Molecular Weight 237.69
  • Synonym(s) None
  • SMILES NCC1=CC=C(C=C1)C2=NN=C(C)N=N2.Cl

Description

Methyltetrazine-amine (hydrochloride) offers a reactive, electron-deficient tetrazine moiety for efficient inverse electron-demand Diels-Alder reactions. This bench-stable derivative features enhanced solubility in aqueous and polar organic media, enabling straightforward conjugation workflows in bioorthogonal labeling and polymer functionalization.

Application

Methyltetrazine-amine (hydrochloride) serves as a versatile bioorthogonal handle, enabling efficient strain-promoted inverse electron-demand Diels-Alder (spIEDDA) reactions with tetrazine ligands. Its enhanced reactivity and hydrophilic character facilitate rapid conjugation under physiological conditions, while the hydrochloride salt improves stability and ease of handling. Ideal for labeling biomolecules and constructing functionalized scaffolds in drug discovery workflows.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS02,GHS07
Signal Word : Danger
UN#: 3175
Class : 4.1
Packing Group : Ⅱ
Hazard Statements : H315-H319-H335-H242
Precautionary Statements : P210-P220-P234-P280-P370+P378-P403+P235-P420-P501

Quality Control

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Computational Chemistry Data

  • TPSA   77.58
  • LogP   1.12252
  • H_Acceptors   5
  • H_Donors   1
  • Rotatable_Bonds   2

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