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CS-W001157 4
Total: USD 88.00

3-Amino-4-bromothiophene-2-carboxamide

  • CAS No. 1378876-49-3

  • Cat. No. CS-0161145
  • Purity≥95%
  • MDL No.MFCD09998834

*For research and further manufacturing use only, not for direct human use.

3-Amino-4-bromothiophene-2-carboxamide|CS-0161145

Structure of 1378876-49-3

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General Information

  • CAS No. 1378876-49-3
  • Cat. No. CS-0161145
  • Purity ≥95%
  • MDL No. MFCD09998834
  • Storage RT, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₅BrN₂OS
  • Molecular Weight 221.08
  • Synonym(s) 3-Amino-4-bromo-2-thiophenecarboxamide
  • SMILES O=C(C1=C(N)C(Br)=CS1)N

Description

3-Amino-4-bromothiophene-2-carboxamide features a brominated thiophene core with strategically positioned amino and carboxamide groups, enabling direct integration into heterocyclic scaffolds. This bench-stable compound serves as a key intermediate for synthesizing bioactive molecules in medicinal chemistry and materials science applications.

Application

3-Amino-4-bromothiophene-2-carboxamide serves as a versatile building block in medicinal chemistry, enabling efficient access to functionalized thiophene scaffolds. The amino and carboxamide groups provide orthogonal handles for coupling reactions, while the bromine facilitates palladium-catalyzed cross-couplings. Its bench-stable nature and compatibility with standard purification methods make it ideal for multi-step synthesis of heterocyclic compounds and API intermediates.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P280-P302+P352

Quality Control

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Computational Chemistry Data

  • TPSA   69.11
  • LogP   1.1917
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   1

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