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Structure of 137129-98-7
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6-Chloro-2-methylnicotinic acid features a chlorine substituent at the 6-position and a methyl group at the 2-position of the nicotinic acid scaffold. This electron-deficient heterocycle serves as a key building block in medicinal chemistry, enabling direct incorporation into bioactive molecules through amidation or esterification. The combination of steric and electronic modulation enhances metabolic stability and target engagement in pharmaceutical development workflows.
6-Chloro-2-methylnicotinic acid serves as a versatile building block in medicinal chemistry, enabling the synthesis of bioactive heterocycles and pharmaceutical intermediates. Its ortho-substituted pyridine core provides enhanced reactivity for downstream functionalization, while the chloro and methyl groups offer defined regiochemical control. The compound exhibits good bench stability and facilitates efficient coupling reactions, making it well-suited for scale-up applications in API development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: