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3-(Azepan-1-yl)propanoic acid hydrochloride

  • CAS No. 136671-92-6

  • Cat. No. CS-0445324
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

3-(Azepan-1-yl)propanoic acid hydrochloride|CS-0445324

Structure of 136671-92-6

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General Information

  • CAS No. 136671-92-6
  • Cat. No. CS-0445324
  • Purity ≥97%
  • MDL No. None
  • Storage Store at room temperature, keep dry and cool
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₈ClNO₂
  • Molecular Weight 207.70
  • Synonym(s) 3-(1-azepanyl)propanoic acid hydrochloride
  • SMILES O=C(O)CCN1CCCCCC1.Cl

Description

This bench-stable, moisture-tolerant zwitterionic acid features a tertiary amine-bearing aliphatic chain that enables efficient coupling in peptide synthesis and conjugation workflows. The hydrochloride salt form enhances solubility in aqueous and polar organic media while maintaining structural integrity under standard reaction conditions.

Application

3-(Azepan-1-yl)propanoic acid hydrochloride serves as a versatile building block for bioactive molecule synthesis, enabling the incorporation of a lipophilic, nitrogen-containing aliphatic chain. The azepane ring offers enhanced metabolic stability and modulates physicochemical properties, while the carboxylic acid functionality facilitates amide coupling and esterification under standard conditions. Its hydrochloride salt form enhances solubility and handling stability, supporting efficient purification and integration into medicinal chemistry workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   40.54
  • LogP   1.7589
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   3

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