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Structure of 1361380-69-9
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This boronate moiety features a trifluoromethyl-substituted pyrazole scaffold, delivering enhanced stability and solubility in polar solvents. The isopropyl group imparts steric protection, minimizing protodeboronation under standard conditions. Ideal for Suzuki-Miyaura cross-coupling reactions, this reagent enables efficient construction of complex heteroaryl architectures with minimal side-product formation.
(1-Isopropyl-3-(trifluoromethyl)-1H-pyrazol-5-yl)boronic acid serves as a versatile building block in Suzuki-Miyaura cross-coupling reactions, enabling efficient C–C bond formation under mild conditions. The trifluoromethyl group enhances metabolic stability and lipophilicity, while the isopropyl substituent provides steric bulk and improved solubility. Bench-stable and compatible with diverse functional groups, it facilitates rapid access to complex pyrazole-based scaffolds relevant to medicinal chemistry and agrochemical research.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: