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CS-W001157 4
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(1,3-Dimethyl-1H-pyrazol-5-yl)boronic acid

  • CAS No. 847818-68-2

  • Cat. No. CS-0109835
  • Purity≥95%
  • MDL No.MFCD12407383

*For research and further manufacturing use only, not for direct human use.

(1,3-Dimethyl-1H-pyrazol-5-yl)boronic acid|CS-0109835

Structure of 847818-68-2

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General Information

  • CAS No. 847818-68-2
  • Cat. No. CS-0109835
  • Purity ≥95%
  • MDL No. MFCD12407383
  • Storage -20°C, sealed storage, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₉BN₂O₂
  • Molecular Weight 139.95
  • Synonym(s) 1,3-Dimethylpyrazole-5-boronic acid
  • SMILES OB(C1=CC(C)=NN1C)O

Description

This boronate moiety integrates readily into Suzuki-Miyaura cross-coupling reactions under standard conditions, delivering functionalized heterocycles with high efficiency. The dimethylpyrazole scaffold imparts enhanced solubility and stability, enabling straightforward handling in synthetic workflows.

Application

(1,3-Dimethyl-1H-pyrazol-5-yl)boronic acid serves as a stable, bench-friendly building block for Suzuki-Miyaura cross-coupling reactions. Its pyrazole core offers enhanced functional group tolerance and facilitates the construction of biologically relevant heterocyclic scaffolds. The boronic acid moiety enables reliable coupling with aryl and vinyl halides under mild conditions, supporting efficient synthesis of complex molecular architectures in medicinal chemistry and materials science applications.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   58.28
  • LogP   -1.59168
  • H_Acceptors   4
  • H_Donors   2
  • Rotatable_Bonds   1

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