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CS-W001157 4
Total: USD 88.00

4-Methyl-3-thiopheneboronic acid

  • CAS No. 177735-11-4

  • Cat. No. CS-0152844
  • Purity≥95%
  • MDL No.MFCD04039882

*For research and further manufacturing use only, not for direct human use.

4-Methyl-3-thiopheneboronic acid|CS-0152844

Structure of 177735-11-4

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General Information

  • CAS No. 177735-11-4
  • Cat. No. CS-0152844
  • Purity ≥95%
  • MDL No. MFCD04039882
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₇BO₂S
  • Molecular Weight 141.98
  • Synonym(s) (4-Methyl-3-thienyl)boronic acid
  • SMILES CC1=CSC=C1B(O)O

Description

4-Methyl-3-thiopheneboronic acid features a boronate moiety integrated into a thiophene scaffold, enabling efficient Suzuki-Miyaura coupling under standard conditions. The methyl substituent enhances electronic stability and improves solubility in polar organic solvents. This bench-stable reagent facilitates the construction of functionalized heteroaromatic architectures with high regiocontrol.

Synthesis

  • Route1

    References

    • ELI LILLY AND COMPANY Patent: WO2006/102194 A1, 2006 ; Location in patent: Page/Page column 39 ; WO 2006/102194 A1

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H332-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   40.46
  • LogP   -0.26368
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   1

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