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CS-W001157 4
Total: USD 88.00

(5-Methylbenzo[b]thiophen-2-yl)boronic acid

  • CAS No. 136099-65-5

  • Cat. No. CS-0175860
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

(5-Methylbenzo[b]thiophen-2-yl)boronic acid|CS-0175860

Structure of 136099-65-5

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General Information

  • CAS No. 136099-65-5
  • Cat. No. CS-0175860
  • Purity ≥98%
  • MDL No. None
  • Storage -20°C, sealed storage, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₉BO₂S
  • Molecular Weight 192.04
  • Synonym(s) 5-Methylbenzo[b]thiophene-2-boronic acid
  • SMILES CC1=CC2=C(SC(B(O)O)=C2)C=C1

Description

This boronate moiety integrates seamlessly into Suzuki-Miyaura cross-coupling reactions, delivering robust yields under standard conditions. The methyl-substituted benzothiophene scaffold enhances stability and solubility, enabling efficient access to complex heterocyclic architectures in medicinal chemistry and materials science applications.

Application

(5-Methylbenzo[b]thiophen-2-yl)boronic acid serves as a versatile building block in Suzuki-Miyaura cross-coupling reactions, enabling efficient construction of biaryl and heteroaryl architectures. Its bench-stable boronic acid functionality exhibits excellent functional group tolerance and facilitates straightforward purification, making it well-suited for iterative synthesis in medicinal chemistry and materials science applications.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362-P405-P501

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Computational Chemistry Data

  • TPSA   40.46
  • LogP   0.88952
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   1

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