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Structure of 1354951-46-4
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This difluoromethoxy-substituted aniline derivative features a hydrochloride salt form that enhances solubility and stability. The para-fluoro and ortho-difluoromethoxy groups confer electron-withdrawing character, enabling effective integration into pharmaceutical intermediates and bioactive molecule scaffolds under standard conditions.
(2-(Difluoromethoxy)-6-fluorophenyl)methanamine hydrochloride serves as a valuable building block for the synthesis of fluorinated aromatic amines, enabling efficient access to bioactive scaffolds in medicinal chemistry. Its difluoromethoxy and fluorophenyl functionalities provide enhanced metabolic stability and modulated lipophilicity. The hydrochloride salt ensures excellent bench stability, ease of handling, and straightforward purification, facilitating its use in standard amine coupling, electrophilic substitution, and heterocycle construction workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: