Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

(6-(Difluoromethoxy)pyridin-3-yl)boronic acid

  • CAS No. 1354290-88-2

  • Cat. No. CS-0107244
  • Purity≥97%
  • MDL No.MFCD18261896

*For research and further manufacturing use only, not for direct human use.

(6-(Difluoromethoxy)pyridin-3-yl)boronic acid|CS-0107244

Structure of 1354290-88-2

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 1354290-88-2
  • Cat. No. CS-0107244
  • Purity ≥97%
  • MDL No. MFCD18261896
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₆BF₂NO₃
  • Molecular Weight 188.92
  • Synonym(s) None
  • SMILES FC(F)OC1=CC=C(B(O)O)C=N1

Description

This boronate moiety features a difluoromethoxy-substituted pyridine core, delivering enhanced stability and solubility in polar solvents. The electron-deficient pyridine ring facilitates efficient Suzuki-Miyaura coupling, while the bench-stable boronic acid group enables reliable cross-coupling under standard conditions.

Application

(6-(Difluoromethoxy)pyridin-3-yl)boronic acid serves as a versatile building block in Suzuki-Miyaura coupling reactions, enabling efficient C–C bond formation under mild conditions. The difluoromethoxy group imparts enhanced metabolic stability and modulates electronic properties, making this scaffold valuable for medicinal chemistry applications. Bench-stable and readily purified by recrystallization, it exhibits broad functional group tolerance and compatibility with standard cross-coupling protocols.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   62.58
  • LogP   -0.6372
  • H_Acceptors   4
  • H_Donors   2
  • Rotatable_Bonds   3

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 1354290-88-2 sigma1354290-88-2 manufacturer1354290-88-2 price1354290-88-2 structure1354290-88-2 SDSbuy 1354290-88-21354290-88-2 supplier1354290-88-2 uses1354290-88-2 molecular weightprice of 1354290-88-21354290-88-2 chemical name formula of 1354290-88-2
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label