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CS-W001157 4
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5-Chloro-3-iodo-1H-pyrazolo[3,4-b]pyridine

  • CAS No. 1352395-64-2

  • Cat. No. CS-0157359
  • Purity≥96%
  • MDL No.MFCD20923268

*For research and further manufacturing use only, not for direct human use.

5-Chloro-3-iodo-1H-pyrazolo[3,4-b]pyridine|CS-0157359

Structure of 1352395-64-2

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General Information

  • CAS No. 1352395-64-2
  • Cat. No. CS-0157359
  • Purity ≥96%
  • MDL No. MFCD20923268
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₃ClIN₃
  • Molecular Weight 279.47
  • Synonym(s) None
  • SMILES C1=C(C=NC2=NNC(=C12)I)Cl

Synthesis

  • Route1

    References

    • VERTEX PHARMACEUTICALS INCORPORATED; CHARIFSON, Paul, S.; CLARK, Michael, P.; BANDARAGE, Upul, K.; DAVIES, Ioana; DUFFY, John, P.; GAO, Huai; FENG, Jun; LIANG, Jianglin; KENNEDY, Joseph, M.; LEDEBOER, Mark, W.; LEDFORD, Brian; MALTAIS, Francois; PEROLA, Emanuele Patent: WO2012/83117 A1, 2012 ; Location in patent: Page/Page column 122 ;
  • Route2

    References

    • VERTEX PHARMACEUTICALS INCORPORATED; CHARIFSON, Paul, S.; CLARK, Michael, P.; BANDARAGE, Upul, K.; DAVIES, Ioana; DUFFY, John, P.; GAO, Huai; FENG, Jun; LIANG, Jianglin; KENNEDY, Joseph, M.; LEDEBOER, Mark, W.; LEDFORD, Brian; MALTAIS, Francois; PEROLA, Emanuele Patent: WO2012/83117 A1, 2012 ;
  • Route3
    • 5-Chloro-2-fluoro-3-(4,4,5,5-tetramethyl-1,3-dioxolan-2-yl)pyridine|CS-0194691
      1383446-21-6
    • ~%
    • In-stock
      5-Chloro-3-iodo-1H-pyrazolo[3,4-b]pyridine|CS-0157359
      1352395-64-2

    References

    • VERTEX PHARMACEUTICALS INCORPORATED; CHARIFSON, Paul, S.; CLARK, Michael, P.; BANDARAGE, Upul, K.; DAVIES, Ioana; DUFFY, John, P.; GAO, Huai; FENG, Jun; LIANG, Jianglin; KENNEDY, Joseph, M.; LEDEBOER, Mark, W.; LEDFORD, Brian; MALTAIS, Francois; PEROLA, Emanuele Patent: WO2012/83117 A1, 2012 ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   41.57
  • LogP   2.2159
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   0

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