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Bis-propargyl-PEG11

  • CAS No. 1351373-49-3

  • Cat. No. CS-0115584
  • Molecule weight578.69
  • Purity≥97%
  • MDL No.MFCD32207028

*For research and further manufacturing use only, not for direct human use.

Bis-propargyl-PEG11|CS-0115584

Structure of 1351373-49-3

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General Information

  • CAS No. 1351373-49-3
  • Cat. No. CS-0115584
  • Purity ≥97%
  • MDL No. MFCD32207028
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₂₈H₅₀O₁₂
  • Molecular Weight 578.69
  • Synonym(s) None
  • SMILES C#CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCC#C

Description

Bis-propargyl-PEG11 features two terminal propargyl groups flanking an 11-ethylene glycol unit, enabling efficient copper-catalyzed azide-alkyne cycloaddition. This bifunctional linker offers enhanced solubility in aqueous and organic media, facilitating conjugation workflows in bioconjugation and polymer synthesis.

Application

Bis-propargyl-PEG11 serves as a versatile, linear spacer for click chemistry applications, enabling efficient copper-catalyzed azide-alkyne cycloaddition (CuAAC) at both termini. Its PEG backbone provides enhanced solubility and biocompatibility, while the terminal propargyl groups offer high reactivity and stability under standard bench conditions. Ideal for synthesizing dendrimers, cross-linking polymers, or constructing bioconjugates with precise spacing and functional group tolerance.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   110.76
  • LogP   0.452
  • H_Acceptors   12
  • H_Donors   0
  • Rotatable_Bonds   35

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