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Total: USD 88.00

Bis-propargyl-PEG3

  • CAS No. 126422-58-0

  • Cat. No. CS-0113214
  • Purity≥98%
  • MDL No.MFCD22683298

*For research and further manufacturing use only, not for direct human use.

Bis-propargyl-PEG3|CS-0113214

Structure of 126422-58-0

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General Information

  • CAS No. 126422-58-0
  • Cat. No. CS-0113214
  • Purity ≥98%
  • MDL No. MFCD22683298
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₂H₁₈O₄
  • Molecular Weight 226.27
  • Synonym(s) None
  • SMILES C#CCOCCOCCOCCOCC#C

Description

Bis-propargyl-PEG3 features two propargyl groups flanking a triethylene glycol spacer, enabling efficient copper-catalyzed azide-alkyne cycloaddition (CuAAC) for bioconjugation. This bifunctional linker offers enhanced solubility in aqueous and organic media, with stable performance under standard bench conditions. Ideal for constructing molecular architectures in drug delivery and polymer science.

Application

Bis-propargyl-PEG3 serves as a versatile bifunctional linker for copper-catalyzed azide-alkyne cycloaddition (CuAAC) reactions, enabling efficient conjugation of biomolecules and functional materials. Its PEG3 spacer provides enhanced solubility and reduced aggregation, while the terminal propargyl groups offer high reactivity and compatibility with standard click chemistry protocols. Ideal for modular synthesis of dendrimers, bioconjugates, and surface-functionalized nanoparticles.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   36.92
  • LogP   0.3192
  • H_Acceptors   4
  • H_Donors   0
  • Rotatable_Bonds   11

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